BDBM33252 phthalazine-based compound, 3

SMILES C1CCC2N=C(NC2C1)c1ccc(Nc2nnc(Nc3ccc(cc3)C3=NC4CCCCC4N3)c3ccccc23)cc1

InChI Key InChIKey=KXZYDMCZMIXCEE-UHFFFAOYSA-N

Data  5 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 33252   

TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33252(phthalazine-based compound, 3)
Affinity DataIC50:  1.10E+3nM Kd:  7.70E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed