BDBM50263168 CHEMBL476351::N-[4'-(Cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-2-morpholin-4-yl-isonicotinamide::N-{4'-[(cyclopropylmethyl)carbamoyl]-6-methylbiphenyl-3-yl}-2-morpholin-4-ylpyridine-4-carboxamide

SMILES Cc1ccc(NC(=O)c2ccnc(c2)N2CCOCC2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key InChIKey=BOQNSWFZUHQNRG-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263168   

TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263168(CHEMBL476351 | N-[4'-(Cyclopropylmethyl-carbamoyl)...)
Affinity DataIC50:  27nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed