BDBM50436850 CERITINIB::CHEMBL2403108::LDK378::US10053458, Comparative Example 2::US10618884, Example 16::US9809572, Example 16
SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI Key InChIKey=VERWOWGGCGHDQE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50436850
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) using peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of cMET (unknown origin) after 60 minsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of TEL-fused MET (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged c-MET cytoplasmic domain (956 to 1390 residues) expressed in baculovirus expression system usin...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 271nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MET (956 to 1390 residues) cytoplasmic domain expressed in baculovirus expression system using ...More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of c-Met (unknown origin) using peptide substrate incubated for 60 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair