BDBM50601551 CHEMBL5207281
SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCCCCNC(=O)\N=C(/N)NCCCc1nnc(N)s1
InChI Key InChIKey=WPIVDYCRNVUSIY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50601551
Affinity DataKi: 3nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
Affinity DataEC50: 5.80nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Agonist activity at guinea pig histamine H2 receptor stably transfected in HEK293T cells co-expressing NlucN-mGs/gpH2R-NlucC by mini-G protein recrui...More data for this Ligand-Target Pair
Affinity DataEC50: 5.60nMAssay Description:Agonist activity at histamine H2 receptor in spontaneous beating guinea pig right atrium assessed as increase in heart beatMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S incubated for 90...More data for this Ligand-Target Pair
Affinity DataEC50: 234nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing ARRB2 incubated for 60 mins by beta-arrestin2 recruit...More data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair