BDBM50555461 CHEMBL4749655

SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncn(CCCCCCC(=O)NO)c2n1

InChI Key InChIKey=JBFFDSGEOZGWCK-UHFFFAOYSA-N

Data  27 IC50  5 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50555461   

TargetHistone deacetylase 1(Homo sapiens (Human))
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50555461(CHEMBL4749655)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full-length HDAC1 (unknown origin) by Color-de-Lys assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50555461(CHEMBL4749655)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of HDAC1 in human HeLa nuclear extract using Boc-Lys(Ac)-AMC as substrate measured after 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Bioland Laboratory (Guangzhou Regenerative Medicine And Health - Guangdong Laboratory)

Curated by ChEMBL
LigandPNGBDBM50555461(CHEMBL4749655)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 end residues) expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed