BDBM50505772 CHEMBL4589062

SMILES Cc1ccccc1NC(=O)N1C(CC(O)=O)CC1=O

InChI Key InChIKey=NMHXECODTXNHIV-UHFFFAOYSA-N

Data  11 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505772   

TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta5 in human MCF7 cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)
Affinity DataIC50: >5.00E+3nMAssay Description:Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed