BDBM279664 US10035797, Compound 3::US10428068, Compound 3::US10844056, Compound 3::US11560377, Compound 3::US9630965, Compound 3

SMILES Nc1nccc2n(CCCC#C)c(Sc3cc4OCOc4cc3I)nc12

InChI Key InChIKey=SQZKQANWVCAAJZ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279664   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Curis

US Patent
LigandPNGBDBM279664(US10035797, Compound 3 | US10428068, Compound 3 | ...)
Affinity DataIC50:  550nMAssay Description:The Hsp90 chaperone assay was performed to measure the ability of HSP90 protein to refold the heat-denatured luciferase protein. HSP90 was first incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent