BDBM223543 US9321748, 3

SMILES CN1CCc2cc(ccc12)-c1cnc(N)c(c1)-c1nnc(o1)C1CC1

InChI Key InChIKey=TUCDQEPFNWGJGE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223543   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223543(US9321748, 3)
Affinity DataIC50:  970nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM223543(US9321748, 3)
Affinity DataIC50:  970nMAssay Description:Inhibition of recombinant human wild type GST-tagged LRRK2 (970 to 2527 residues) preincubated for 30 mins followed by fluorescein-LRRKtide substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed