BDBM50503878 CHEMBL4463203

SMILES CCCCc1nc(Cl)c(CNC(=O)[C@H](CS)CC(C)C)n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key InChIKey=XRWGWRHXWJHKMY-QFIPXVFZSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50503878   

TargetNeprilysin(Homo sapiens (Human))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50503878(CHEMBL4463203)
Affinity DataIC50:  40nMAssay Description:Inhibition of NEP (unknown origin) preincubated for 10 mins followed by fluorogenic substrate addition and measured after 20 mins by fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed