BDBM50322529 (2S,3S)-2-(3-Fluorophenyl)-3,5,5-trimethylmorpholin-2-ol::CHEMBL1173275
SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(F)c1
InChI Key InChIKey=NNTJAYKRPQPBCZ-TVQRCGJNSA-N
Data 13 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50322529
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Barrow Neurological Institute
Curated by ChEMBL
Barrow Neurological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at alpha4beta4 nicotinic receptor in human SH-EP1 cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx at...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Barrow Neurological Institute
Curated by ChEMBL
Barrow Neurological Institute
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Antagonist activity at human alpha4beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair