BindingDB BDBM259459 US9512114, 24::US9657007, Example 24

BDBM259459 US9512114, 24::US9657007, Example 24

SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key InChIKey=TVNBFTHHLHAUSF-JTQLQIEISA-N

Data 8 IC50

Found 1 hit for monomerid = 259459

BDBM259459(US9512114, 24 | US9657007, Example 24)

Targets 7▿
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 1
- Phosphatidylinositol 3-kinase regulatory subunit alpha 1
Publications 2▿
- US Patent US9657007 (2017) 4
- US Patent US9512114 (2016) 4
Institutions 1▿
- Calitor Sciences 8
Affinity: 3 to 3.1E+2 nM▿
- IC50 8
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0