BDBM50447094 CHEMBL1972466

SMILES CC(Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1

InChI Key InChIKey=CPRAGQJXBLMUEL-UHFFFAOYSA-N

Data  19 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50447094   

LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of N-terminal His-tagged human p110alpha expressed in Sf9 cells co-expressing p85alpha regulatory subunit using phosphatidylinositol subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50447094(CHEMBL1972466)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kalpha expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed