BDBM24566 2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidin-2-yl}sulfanyl)acetic acid::CHEMBL295416::JMC515449 Compound 1::Pirinixic acid::Wyeth 14,643

SMILES Cc1cccc(Nc2cc(Cl)nc(SCC(O)=O)n2)c1C

InChI Key InChIKey=SZRPDCCEHVWOJX-UHFFFAOYSA-N

Data  3 KI  10 IC50  6 Kd  64 EC50  2 Koff  1 Other

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24566   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)
Affinity DatapH: 7.4 T: 2°CAssay Description:For assays of intact cells, 5000,000 freshly isolated PMNL cells were resuspended in PGC buffer. After preincubation with the test compounds for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed