BDBM50370682 SOLIFENACIN

SMILES [H]C12CCN(CC1)C[C@@H]2OC(=O)N1CCc2ccccc2[C@@H]1c1ccccc1

InChI Key InChIKey=FBOUYBDGKBSUES-VXKWHMMOSA-N

Data  8 KI  9 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50370682   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

LigandBDBM50370682(SOLIFENACIN)Copy SMILESCopy InChI

Affinity DataIC50:  270nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseDrugBankMCE
PC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

LigandBDBM50370682(SOLIFENACIN)Copy SMILESCopy InChI

Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseDrugBankMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))TBA

LigandBDBM50370682(SOLIFENACIN)Copy SMILESCopy InChI

Affinity DataIC50:  251nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseDrugBankMCE
PC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI