BDBM50242630 CHEMBL4089522

SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCN(CC2)c2ccc(F)cc2)c1

InChI Key InChIKey=UOHKZMQXEJGUES-HJWRWDBZSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242630   

TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  700nMAssay Description:Inhibition of full length recombinant His6-tagged PARP14 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242630(CHEMBL4089522)
Affinity DataIC50:  708nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed