BDBM50173330 CHEMBL3808657::US10023564, Example 13

SMILES CC1=C(C(NC(=O)N1)c1ccc(F)c(c1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=VUCAOBMPSJTWFL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173330   

TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173330(CHEMBL3808657 | US10023564, Example 13)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of GRK1 (unknown origin) using tubulin as substrate by SDS-PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRhodopsin kinase GRK1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50173330(CHEMBL3808657 | US10023564, Example 13)
Affinity DataIC50: >1.00E+5nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
In DepthDetails US Patent