BDBM50240985 CHEMBL4089567
SMILES Nc1ccc(cc1)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
InChI Key InChIKey=OGMSQGCPVLGNIG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50240985
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataKi: 396nMAssay Description:Inhibition of human C-terminal GST-tagged mTOR (1360 to 2549 residues) expressed in baculovirus expression system using after 1 hr AlexaFluor647-labe...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University of Basel
Curated by ChEMBL
University of Basel
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of mTOR in human A2058 cells assessed as reduction in phosphorylation of S6 at ser235/236 residues after 1 hr by in-cell Western methodMore data for this Ligand-Target Pair