BDBM50464622 CHEMBL4280423::US11091476, Example 7

SMILES CCC1(C)C(C)=Nc2c1cc(cc2F)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F

InChI Key InChIKey=IDNJKMAZNUUVIO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464622   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Gan & Lee Pharmaceuticals

US Patent
LigandPNGBDBM50464622(CHEMBL4280423 | US11091476, Example 7)
Affinity DataIC50:  461nMAssay Description: 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent