BDBM50268440 2-(2,4-dichlorophenyl)-1-(6-(methylsulfonyl)spiro[chroman-2,4'-piperidine]-1'-yl)ethanone::CHEMBL497829

SMILES CS(=O)(=O)c1ccc2OC3(CCN(CC3)C(=O)Cc3ccc(Cl)cc3Cl)CCc2c1

InChI Key InChIKey=RTSHWIRSEUIDML-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268440   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50268440(2-(2,4-dichlorophenyl)-1-(6-(methylsulfonyl)spiro[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Voltage-gated sodium channel subunit alpha Nav1.5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed