BDBM22167 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine::CHEMBL26320::CHEMBL434080::GBR 12935::GBR-12935
SMILES C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
InChI Key InChIKey=RAQPOZGWANIDQT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 22167
Affinity DataKi: 620nM ΔG°: -7.87kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Binding affinity against serotonin transporter using [125]RTI-55More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Binding affinity for serotonin transporterMore data for this Ligand-Target Pair
Affinity DataKi: 623nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]-RTI-55 in rat.More data for this Ligand-Target Pair
Affinity DataKi: 623nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 623nMAssay Description:Binding affinity for serotonin transporter (SERT)More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataKi: 2.09E+3nMAssay Description:Binding affinity for serotonin transporter using [125I]RTI-55More data for this Ligand-Target Pair
Affinity DataIC50: 623nMAssay Description:Binding affinity was determined at the Serotonin transporter labeled with radioligand [125 I] RTI-55More data for this Ligand-Target Pair
Affinity DataIC50: 289nMAssay Description:Inhibition of [3H]5-HT reuptake at rat serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 289nMAssay Description:Compound was tested for its ability to inhibit the uptake of Serotonin in Serotonin transporter systemMore data for this Ligand-Target Pair
Affinity DataIC50: 298nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair