BDBM50585516 CHEMBL5075673

SMILES [H][C@]12CC[C@]([H])(C[C@H](C1)Nc1cc(cc3cnc(N)nc13)-c1cc(F)c(O)cc1CC)N2

InChI Key InChIKey=OOSFLRHKSBTYIX-BJWYYQGGSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50585516   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Gsk

Curated by ChEMBL
LigandPNGBDBM50585516(CHEMBL5075673)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of GST-fused human JAK3 (810 to 1100 residues) expressed in insect cells using ULight-JAK-1 Tyr1023 peptide as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed