BDBM50236238 (3alpha,5beta)-3-hydroxycholan-24-oic acid::3alpha-hydroxy-5beta-cholan-24-oic acid::3alpha-hydroxy-5beta-cholanic acid::3alpha-hydroxy-5beta-cholanoic acid::5beta-cholanic acid-3alpha-ol::CHEMBL1478::LCA::cid_9903::lithocholic acid
SMILES C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI Key InChIKey=SMEROWZSTRWXGI-HVATVPOCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50236238
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataKd: 330nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD canonical site (118 to 427) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataKd: 9.52E+3nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD low-affinity site (118 to 427) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataKd: 1.89E+4nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD (118 to 427) by reverse isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at VDR-LBD (unknown origin) expressed in Escherichia coli assessed as SRC2-3 coactivator peptide recruitment after 30 mins by fluore...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataIC50: 1.36E+4nMAssay Description:Agonist activity at VDR-LBD (unknown origin) expressed in Escherichia coli assessed as SRC2-3 coactivator peptide recruitment after 30 mins by fluore...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataEC50: 2.14E+3nMAssay Description:Agonist activity at VDR-LBD (unknown origin) expressed in Escherichia coli assessed as SRC2-3 coactivator peptide recruitment after 30 mins by fluore...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)
Curated by ChEMBL
Affinity DataIC50: 4.67E+4nMAssay Description:Antagonist activity against VDR-LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of VDR agonist LG190178-induced SRC2-3 coac...More data for this Ligand-Target Pair