BDBM186815 US9670203, Compound 1.7
SMILES Cc1cc(Cl)ccc1NC(=O)N[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12
InChI Key InChIKey=UMEZSNVGJGZDSS-VABKMULXSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 186815
TargetRAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D](Human)
Beigene
US Patent
Beigene
US Patent
Affinity DataIC50: 350nMT: 25°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMT: 25°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair