BDBM50016897 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form)
SMILES Clc1cccc(Cl)c1\[#7]=[#6]-1\[#7]-[#6]-[#6]-[#7]-1
InChI Key InChIKey=GJSURZIOUXUGAL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50016897
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
TargetMultidrug and toxin extrusion protein 1(Homo sapiens (Human))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.93E+4nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.2 uM) in OCT3-expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Inhibition of Sprague-Dawley rat imidazoline I1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 366nMAssay Description:Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair