BDBM15581 CHEMBL8706::CLG::CLORGILINE::Clorgyline::N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine::US8633208, Clorgyline::US9603833, Clorgyline::[3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine
SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C
InChI Key InChIKey=BTFHLQRNAMSNLC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 15581
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Soochow University
Curated by ChEMBL
Soochow University
Curated by ChEMBL
Affinity DataKi: 2.90nMAssay Description:Inhibition of radioligand binding to sigma1 receptor in C57BL/6 mouse brain membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Medical College of Georgia
Curated by PDSP Ki Database
Medical College of Georgia
Curated by PDSP Ki Database
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Reversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of bovine brain MAOA using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibitory activity against monoamine oxidase A in isolated bovine brain mitochondriaMore data for this Ligand-Target Pair
Affinity DataKi: 54nM ΔG°: -10.3kcal/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Inhibition of bovine brain mitochondrial MAO-A by fluorometric assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Irreversible inhibition of recombinant human MAOA expressed in Pichia pastoris using varying levels of kynuramine as substrate measured after 5 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 505nMAssay Description:Inhibition of radioligand binding to sigma2 receptor in C57BL/6 mouse brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University of Turku
Curated by PDSP Ki Database
University of Turku
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University of Turku
Curated by PDSP Ki Database
University of Turku
Curated by PDSP Ki Database
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Hacettepe University
Curated by ChEMBL
Hacettepe University
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-EFC O-deethylation activityMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Hacettepe University
Curated by ChEMBL
Hacettepe University
Curated by ChEMBL
Affinity DataKi: 5.60E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of bovine brain mitochondrial MAO-B by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of bovine brain MAOB using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
Affinity DataKi: 5.80E+4nMAssay Description:Inhibitory activity against monoamine oxidase B in isolated bovine brain mitochondriaMore data for this Ligand-Target Pair