BDBM25116 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL306380::PP1::US10688093, Compound PP1 (Pfizer)::US10807986, Comparative compound 1::US11046696, Compound 1 of Comparative Examples::US11701353, PP1 (Pfizer)::cid_1400
SMILES Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C
InChI Key InChIKey=ZVPDNRVYHLRXLX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 25116
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee
Curated by PDSP Ki Database
University of Dundee
Curated by PDSP Ki Database
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University of Dundee
Curated by PDSP Ki Database
University of Dundee
Curated by PDSP Ki Database
Affinity DataKi: 790nMAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
University of Dundee
Curated by PDSP Ki Database
University of Dundee
Curated by PDSP Ki Database
Affinity DataKi: >2.00E+4nMAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-6.34kcal/molepH: 7.5 T: 2°CAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nM ΔG°: >-6.34kcal/molepH: 7.5 T: 2°CAssay Description:Kinase was assayed in 384-well polypropylene plate format. The compound was mixed with kinase and biotinylated peptide substrate and incubated. After...More data for this Ligand-Target Pair