BDBM104499 US8575114, I-11
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cn2nc3ccc(F)cn3c2=O)c1
InChI Key InChIKey=WZXRBMRWUOIXDN-LHKMKVQPSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 104499
Affinity DataIC50: 222nMAssay Description:The inhibitory activity of the compounds of this invention against the SGLT-1 or SGLT-2 transporters.More data for this Ligand-Target Pair
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 222nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair