BDBM104499 US8575114, I-11

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cn2nc3ccc(F)cn3c2=O)c1

InChI Key InChIKey=WZXRBMRWUOIXDN-LHKMKVQPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104499   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104499(US8575114, I-11)
Affinity DataIC50:  222nMAssay Description:The inhibitory activity of the compounds of this invention against the SGLT-1 or SGLT-2 transporters.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104499(US8575114, I-11)
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM104499(US8575114, I-11)
Affinity DataIC50:  222nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed