BDBM106785 5-Hydroxy-7-benzyl-4′-nitro-isoflavone (4b)::7‐(benzyloxy)‐5‐hydroxy‐3‐(4‐nitrophenyl)‐4H‐ chromen‐4‐one

SMILES Oc1cc(OCc2ccccc2)cc2occ(-c3ccc(cc3)[N+]([O-])=O)c(=O)c12

InChI Key InChIKey=JLYZEAADHQUATL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106785   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106785(5-Hydroxy-7-benzyl-4′-nitro-isoflavone (4b) ...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106785(5-Hydroxy-7-benzyl-4′-nitro-isoflavone (4b) ...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed