BDBM1099 (4R,5R,6R)-Tetrahydro-1,3-bis[(3-cyano-4-fluorophenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::5-{[(4R,5R,6R)-4-benzyl-3-[(3-cyano-4-fluorophenyl)methyl]-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]methyl}-2-fluorobenzonitrile::Tetrahydropyrimidinone deriv. 52
SMILES O[C@@H]1[C@@H](CCc2ccccc2)N(Cc2ccc(F)c(c2)C#N)C(=O)N(Cc2ccc(F)c(c2)C#N)[C@@H]1Cc1ccccc1
InChI Key InChIKey=VDCHURQWRJSKTK-CKOYEXALSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 1099
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 230nM ΔG°: -9.41kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair