BDBM123916 US8754113, A-13

SMILES Fc1c(ccc2nc(Cc3nnc(CC(=O)NC4(CC4)C#N)o3)sc12)-c1ccc(Cl)cc1

InChI Key InChIKey=DWVMLTWOTMSASI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123916   

TargetEndothelial lipase(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM123916(US8754113, A-13)
Affinity DataIC50:  22nMT: 2°CAssay Description:After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...More data for this Ligand-Target Pair
In DepthDetails US Patent