BDBM127079 US8785459, 154

SMILES COc1cc(ccc1O)-c1ccc2ncnc(Nc3cc(O)ccc3C)c2c1

InChI Key InChIKey=FLTWWDWTIZAELE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 127079   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127079(US8785459, 154)
Affinity DataIC50:  60nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127079(US8785459, 154)
Affinity DataIC50:  591nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127079(US8785459, 154)
Affinity DataIC50:  70.9nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent