BDBM130758 US8822448, 182
SMILES C[C@@H]1CN(CCN1c1ccc(F)c(C)n1)C(=O)c1cc2c3n(ncc3c(=O)[nH]c2cc1C)[C@H]1CCN(C)C1
InChI Key InChIKey=LDJGXOYCLAYDMS-MJGOQNOKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 130758
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Rattus norvegicus (Rat))
Astellas Pharma
US Patent
Astellas Pharma
US Patent
Affinity DataIC50: 5.5nMpH: 8.0Assay Description:The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...More data for this Ligand-Target Pair