BDBM130778 US8822448, 207
SMILES C[C@H]1CN(CCN1CCC(F)(F)F)C(=O)c1cc2c3n(ncc3c(=O)[nH]c2cc1C)C1CCOCC1
InChI Key InChIKey=IWTKQTWPBDOWMP-INIZCTEOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 130778
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Rattus norvegicus (Rat))
Astellas Pharma
US Patent
Astellas Pharma
US Patent
Affinity DataIC50: 1.70nMpH: 8.0Assay Description:The PDE9-inhibiting activity was measured by the following method. That is, to a buffer solution containing tris(hydroxymethyl)aminomethane-hydrochlo...More data for this Ligand-Target Pair