BDBM131891 US8835436, Example 100

SMILES COc1ccccc1-n1c(C)nc(C(=O)NCC(O)CN2CCN(CC2)c2cccc(C)c2C)c1C

InChI Key InChIKey=YEQXNYBUJMFQJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 131891   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM131891(US8835436, Example 100)
Affinity DataIC50:  389nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM131891(US8835436, Example 100)
Affinity DataIC50:  12nMpH: 7.4Assay Description:For serotonin transporter binding assays, a reaction mixture with a final volume of 0.25 ml was prepared by mixing a test compound, human serotonin t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

US Patent
LigandPNGBDBM131891(US8835436, Example 100)
Affinity DataIC50:  207nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent