BDBM133559 US11091471, Example RO-251::US8846719, 251

SMILES Cc1onc(c1COc1ccc(cn1)C(=O)NC1CCOCC1)-c1ccc(C)cc1

InChI Key InChIKey=VCAOZNYTIATHLZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133559   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM133559(US11091471, Example RO-251 | US8846719, 251)
Affinity DataKi:  0.900nM ΔG°:  -11.5kcal/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM133559(US11091471, Example RO-251 | US8846719, 251)
Affinity DataKi:  1nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
In DepthDetails US Patent