BDBM14568 N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4-chlorophenyl)-2-oxo-3-[(2-phenylethyl)amino]-1,2-dihydropyrazin-1-yl]acetamide::Pyrazinone Analog 31c

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=BDUTVVFYIRMFAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14568   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14568(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4...)
Affinity DataIC50:  8.88E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

LigandPNGBDBM14568(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4...)
Affinity DataIC50:  200nMAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed