BDBM155536 US9012461, 12
SMILES CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccc(cc2)C2CCNCC2)ncc1C(F)(F)F
InChI Key InChIKey=MXLHPKHELDZSGA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 155536
Affinity DataIC50: 6.30nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMT: 2°CAssay Description:Adult human dermal lymphatic microvascular endothelial cells (HMVEC-dLyAD) (Cat# CC-2810, Lonza) were seeded into clear-bottom, TC treated 12 well pl...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.0Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
Affinity DataKd: 0.920nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair