BDBM16518 2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl)sulfanyl]-2,3-dihydropyridazin-3-one::2-arylpyridazin-3-one, 21

SMILES Cc1cc(Cl)ccc1-n1nc(Sc2ccc(F)cc2F)ccc1=O

InChI Key InChIKey=HUPPBGGBZDOKDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16518   

TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16518(2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...)
Affinity DataIC50:  850nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16518(2-(4-chloro-2-methylphenyl)-6-[(2,4-difluorophenyl...)
Affinity DataIC50:  310nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed