BDBM16529 2-arylpyridazin-3-one, 35::N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino]propyl}piperidine-4-carboxamide

SMILES Clc1ccccc1N(CCCNC(=O)C1CCNCC1)c1ccc(=O)n(n1)-c1ccccc1Cl

InChI Key InChIKey=YRJCGFIHLVCSEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16529   

TargetMitogen-activated protein kinase 11(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16529(2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  29nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM16529(2-arylpyridazin-3-one, 35 | N-{3-[(2-chlorophenyl)...)
Affinity DataIC50:  8nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed