BDBM181749 US9139585, 39A

SMILES C[C@@H]1Cc2cc(ccc2C(=O)O1)[C@@H](O)CN1C[C@@H]2C[C@H]1CN2C[C@H](O)c1ccc2C(=O)OCc2c1C

InChI Key InChIKey=WJAVGKMVVNZROZ-NALINLHWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181749   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM181749(US9139585, 39A)
Affinity DataIC50:  150nMpH: 7.4 T: 2°CAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In DepthDetails US Patent