BDBM19413 CHEMBL211625::N-(2-aminophenyl)-4-{[(3,4-dimethoxyphenyl)amino]methyl}benzamide::benzamide-type inhibitor, 9

SMILES COc1ccc(NCc2ccc(cc2)C(=O)Nc2ccccc2N)cc1OC

InChI Key InChIKey=LMZMJYFRBVPBFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19413   

TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19413(CHEMBL211625 | N-(2-aminophenyl)-4-{[(3,4-dimethox...)
Affinity DataIC50:  440nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19413(CHEMBL211625 | N-(2-aminophenyl)-4-{[(3,4-dimethox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19413(CHEMBL211625 | N-(2-aminophenyl)-4-{[(3,4-dimethox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

LigandPNGBDBM19413(CHEMBL211625 | N-(2-aminophenyl)-4-{[(3,4-dimethox...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed