BDBM19795 (2S)-3,3-dimethyl-1-{3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl}butan-2-yl N-[(3S)-1-(morpholin-4-ylcarbonylamino)-2-oxoheptan-3-yl]carbamate::ketone analog, 3l

SMILES CCCC[C@H](NC(=O)O[C@H](Cn1ccc(n1)-c1ccc(cc1)C(F)(F)F)C(C)(C)C)C(=O)CNC(=O)N1CCOCC1

InChI Key InChIKey=NHQNWNOSFNNJLZ-UKILVPOCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19795   

TargetCathepsin K(Homo sapiens (Human))
Gsk

LigandPNGBDBM19795((2S)-3,3-dimethyl-1-{3-[4-(trifluoromethyl)phenyl]...)
Affinity DataIC50: >250nMpH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed