BDBM20282 4-{[4-(hexylcarbamoyl)-2-(naphthalen-1-yl)-1,3-oxazol-5-yl]methyl}phenoxyphosphonic acid::S3I-M2001
SMILES CCCCCCNC(=O)c1nc(oc1Cc1ccc(OP(O)(O)=O)cc1)-c1cccc2ccccc12
InChI Key InChIKey=NUEVMWXZKGBDPT-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 20282
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 7.90E+4nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 1.59E+5nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of recombinant STAT3 (unknown origin) expressed in baculovirus in Sf9 insect cells assessed as reduction in DNA binding activity with NIH3...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+4nMAssay Description:A screening process evaluated in vitro disruption of STAT3(dimer)-DNA formation through a previously published EMSA based assays, giving a valuable i...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta/3(Mus musculus (mouse))
University of Central Florida College of Medicine
University of Central Florida College of Medicine
Affinity DataIC50: 9.20E+4nMpH: 7.8 T: 2°CAssay Description:STAT proteins were expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with ...More data for this Ligand-Target Pair