BDBM207499 US9260439, 383

SMILES C[C@@]1(CCN(C1)C(=O)[C@]1(F)CCNC1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key InChIKey=SCBXWFXUIJADDY-ZEQRLZLVSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207499   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha [Q431L,Q432E,D433V,Q434L,V435F,V436Q,K437G,E438P]/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Pfizer

US Patent

LigandBDBM207499(US9260439, 383)Copy SMILESCopy InChI

Affinity DataKi: <0.0180nMAssay Description:PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI