BDBM213777 US9284315, 6

SMILES CN1Cc2cnc3ccc(nc3c2N(C1=O)c1cccc(c1)C(F)(F)F)-c1ccc(nc1)[N+]#[C-]

InChI Key InChIKey=RYCKVPWXMTXZTB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213777   

TargetSerine/threonine-protein kinase mTOR(Human)
Zuanzhu Pharma

US Patent
LigandPNGBDBM213777(US9284315, 6)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents {circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 10 mM MgCl2, 1 mM EGTA, 3 mM MnCl, 0.01% Tween-20, 2 mM DT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

LigandPNGBDBM213777(US9284315, 6)
Affinity DataIC50: 33.8nMpH: 7.5 T: 2°CAssay Description:1. Preparation of test reagents{circle around (1)} 1x kinase buffer (50 mM HEPES, pH 7.5, 3 mM MgCl2, 1 mM EGTA, 100 mM NaCl, 0.03% CHAPS, 2 mM DTT);...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent