BDBM222633 US9315491, MTR-0392::US9801888, Compound MTR-0392
SMILES CSc1c(nc(nc1-c1ccncc1)-c1ccc(NC(=O)Nc2ccc(cc2)C(N)=O)cc1)N1CCOCC1
InChI Key InChIKey=ZMULUGHLOBKVSA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 222633
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 19.6nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 19.6nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair