BDBM222649 US9315491, MTR-0443::US9801888, Compound MTR-0443

SMILES CCOC(=O)c1nc(nc(N2CCOCC2)c1OCC)-c1ccc(NC(=O)Nc2ccc(NC(C)=O)nc2)cc1

InChI Key InChIKey=NGRDQJCPRFZOCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222649   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222649(US9315491, MTR-0443 | US9801888, Compound MTR-0443)
Affinity DataIC50:  76.8nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222649(US9315491, MTR-0443 | US9801888, Compound MTR-0443)
Affinity DataIC50:  76.8nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent