BDBM222650 US9315491, MTR-0446::US9801888, Compound MTR-0446
SMILES CCOc1cnc(nc1N1CCOCC1)-c1ccc(NC(=O)Nc2ccncc2)cc1
InChI Key InChIKey=NAZAMDUGVFALKT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 222650
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 56.6nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology
US Patent
Development Center For Biotechnology
US Patent
Affinity DataIC50: 56.6nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair