BDBM222651 US9315491, MTR-0449::US9801888, Compound MTR-0449

SMILES COc1cnc(nc1N1CCOCC1)-c1ccc(NC(=O)Nc2ccc(NS(C)(=O)=O)cc2)cc1

InChI Key InChIKey=WFGFNVOILXWRTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222651   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222651(US9315491, MTR-0449 | US9801888, Compound MTR-0449)
Affinity DataIC50:  79.2nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222651(US9315491, MTR-0449 | US9801888, Compound MTR-0449)
Affinity DataIC50:  79.2nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent