BDBM222655 US9315491, MTR-0455::US9801888, Compound MTR-0455

SMILES O=C(Nc1ccc(cc1)N1CCOCC1=O)Nc1ccc(cc1)-c1ncc(OCCN2CCOCC2)c(n1)N1CCOCC1

InChI Key InChIKey=ZFHHQBNWBRJBBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222655   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222655(US9315491, MTR-0455 | US9801888, Compound MTR-0455)
Affinity DataIC50:  42.3nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM222655(US9315491, MTR-0455 | US9801888, Compound MTR-0455)
Affinity DataIC50:  42.3nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent